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Cell Biology Proteolysis / Ubiquitin Proteasome / Ubiquitin Proteasome

Anti-PSME1抗体(ab3333)

  • Datasheet
Submit a review Q&A (1)References (3)

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Western blot - Anti-PSME1 antibody (ab3333)

    Key features and details

    • Rabbit polyclonal to PSME1
    • Suitable for: WB
    • Reacts with: Mouse
    • Isotype: IgG

    选择批间可重复性更高的重组抗体

    Product image
    Anti-PSME1 antibody [EPR10968(B)] (ab155985)
    • 研究可靠 —— 各批次间结果一致且可重复
    • 长期批量供应 —— 采用重组技术,可实现快速生产
    • 首次实验即可成功 —— 经过大量验证确认了特异性
    • 符合伦理标准 —— 产品不含动物成分

    概述

    • 产品名称

      Anti-PSME1抗体
      参阅全部 PSME1 一抗
    • 描述

      兔多克隆抗体to PSME1
    • 宿主

      Rabbit
    • 特异性

      Detects PSME1 (proteasome activator complex subunit 1).
    • 经测试应用

      适用于: WBmore details
    • 种属反应性

      与反应: Mouse
      预测可用于: Cow, Pig, Cynomolgus monkey
    • 免疫原

      Synthetic peptide corresponding to Human PSME1 aa 5-22.
      Sequence:

      RVQPEAQAKVDVFREDLC


      (Peptide available as ab4949)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • 阳性对照

      • Rat brain extract.
    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid
    • 存放说明

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
    • 存储溶液

      Constituents: 0.1% BSA, 99% PBS
    • Concentration information loading...
    • 纯度

      Immunogen affinity purified
    • 克隆

      多克隆
    • 同种型

      IgG
    • 研究领域

      • Cell Biology
      • Proteolysis / Ubiquitin
      • Proteasome / Ubiquitin
      • Proteasome
      • Microbiology
      • Organism
      • Virus
      • RNA Virus
      • ssRNA positive strand virus
      • SARS Coronavirus

    相关产品

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab3333于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).

    By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.

    说明
    WB
    Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).

    By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.

    靶标

    • 功能

      Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
    • 序列相似性

      Belongs to the PA28 family.
    • Target information above from: UniProt accession Q06323 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • 数据库链接

      • Entrez Gene: 510041 Cow
      • Entrez Gene: 102141082 Cynomolgus monkey
      • Entrez Gene: 19186 Mouse
      • Entrez Gene: 397572 Pig
      • SwissProt: Q4U5R3 Cow
      • SwissProt: P58238 Cynomolgus monkey
      • SwissProt: P97371 Mouse
      • SwissProt: Q64L94 Pig
      • Unigene: 830 Mouse
      see all
    • 别名

      • 11S regulator complex alpha subunit antibody
      • 11S regulator complex subunit alpha antibody
      • 29 kD MCP activator subunit antibody
      • 29kD MCP activator subunit antibody
      • Activator of multicatalytic protease subunit 1 antibody
      • IFI5111 antibody
      • IGUP I-5111 antibody
      • Interferon gamma IEF SSP 5111 antibody
      • Interferon gamma inducible protein 5111 antibody
      • Interferon gamma up regulated I 5111 protein antibody
      • Interferon gamma up-regulated I-5111 protein antibody
      • MGC8628 antibody
      • PA28a antibody
      • PA28alpha antibody
      • Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody
      • Proteasome activator 28 subunit alpha antibody
      • Proteasome activator complex subunit 1 antibody
      • Proteasome activator subunit 1 antibody
      • PSME1 antibody
      • PSME1_HUMAN antibody
      • REG-alpha antibody
      • REGalpha antibody
      see all

    图片

    • Western blot - Anti-PSME1 antibody (ab3333)
      Western blot - Anti-PSME1 antibody (ab3333)

      Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.

    实验方案

    • Western blot protocols

    Click here to view the general protocols

    数据表及文件

    • Datasheet download

      Download

    文献 (3)

    发表研究结果有使用 ab3333?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab3333 被引用在 3 文献中.

    • Donnelly SK  et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol 216:4331-4349 (2017). PubMed: 29061650
    • Glogauer JE  et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). PubMed: 26112922
    • Pla A  et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . PubMed: 24556681

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    Question

    I would like to confirm that ab3333will detect human reg 1 alpha by western blot. Also if not do you have an antibody that will? Thank-you Lisa

    Read More

    Abcam community

    Verified customer

    Asked on Nov 11 2003

    Answer

    Not to the best of my knoweldge. To eliminate all question, I would perform a BLAST search on the immunizing peptide.

    Read More

    Abcam Scientific Support

    回复于 Nov 18 2003

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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