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Published 26 May, 2022
Recombinant proteins are manipulated versions of native proteins produced using recombinant DNA to generate large amounts of a specific protein. The recombinant DNA is cloned into a vector introduced in a specific expression system (eg, mammalian, bacteria, yeast, or insect cells) to support the expression of the gene of interest and the production of the recombinant protein. Specifically, a bioactive protein is a protein that elicits an effect or response in a biological system.
Pure, high-quality proteins with high batch-to-batch consistency are critical for reliable results in biological research. When purchasing a commercially produced recombinant protein, it is also important to consider the expression system used for production. Each protein expression system has different features and applications and is chosen based on the protein type, function, and required yield.
Abcam offers two ranges of bioactive proteins, depending on your needs:
Bioactive grade proteins: ideal for cell culture and functional studies | Premium grade bioactive proteins: ultra-high purity cytokines and growth factors perfect for preclinical cell culture and functional studies |
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Expression system | Uses | Advantages | Limitations |
Mammalian |
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Insect |
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E. coli |
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Yeast |
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Cell free |
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