Anti-Prosurfactant蛋白C抗体(ab167608)
Key features and details
- Mouse polyclonal to Prosurfactant Protein C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Prosurfactant蛋白C抗体
参阅全部 Prosurfactant Protein C 一抗 -
描述
小鼠多克隆抗体to Prosurfactant蛋白C -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Orangutan -
免疫原
Recombinant full length protein corresponding to Human Prosurfactant Protein C aa 1-197.
Database link: NP_003009.1 -
阳性对照
- SFTCP transfected 293T cell lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
-
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab167608于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa.
|
说明 |
---|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. |
靶标
-
功能
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. -
疾病相关
Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2) [MIM:610913]; also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS) [MIM:267450]; also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'. -
序列相似性
Contains 1 BRICHOS domain. -
细胞定位
Secreted > extracellular space > surface film. - Information by UniProt
-
数据库链接
- Entrez Gene: 6440 Human
- Omim: 178620 Human
- SwissProt: P11686 Human
- Unigene: 1074 Human
-
别名
- BRICD6 antibody
- BRICHOS domain containing 6 antibody
- PSP C antibody
see all
图片
数据表及文件
-
Datasheet download
文献 (0)
ab167608 尚未被引用在任何文献中。