Rhodopsin多肽(ab4967)
Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking
描述
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产品名称
Rhodopsin多肽
参阅全部 Rhodopsin 蛋白酶 -
纯度
> 70 % HPLC.
Peptides are analyzed by Reverse-Phase HPLC (RP-HPLC) in order to determine purity. Identities are confirmed by MALDI-MS. -
无动物成分
No -
性质
Synthetic
技术指标
Our Abpromise guarantee covers the use of ab4967 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking
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形式
Lyophilized -
补充说明
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog ab3424. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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复溶>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
常规信息
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别名
- CSNBAD1
- MGC138309
- MGC138311
see all -
功能
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. -
组织特异性
Rod shaped photoreceptor cells which mediates vision in dim light. -
疾病相关
Retinitis pigmentosa 4
Night blindness, congenital stationary, autosomal dominant 1 -
序列相似性
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. -
翻译后修饰
Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
Contains one covalently linked retinal chromophore. -
细胞定位
Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (2)
ab4967 被引用在 2 文献中.
- Spelat R et al. The dual action of glioma-derived exosomes on neuronal activity: synchronization and disruption of synchrony. Cell Death Dis 13:705 (2022). PubMed: 35963860
- Park YM et al. Acute estradiol treatment reduces skeletal muscle protein breakdown markers in early- but not late-postmenopausal women. Steroids 146:43-49 (2019). PubMed: 30928279
