重组大鼠IL-1 alpha蛋白(ab9877)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组大鼠IL-1 alpha蛋白
参阅全部 IL-1 alpha 蛋白酶 -
纯度
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Rat -
序列
Recombinant Rat IL-1a is a 17.7 kDa protein containing 155 amino acid residues: MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYV DMDRIH LKAASLNDLQ LEVKFDMYAYSSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKNYFTSAAF PEL LIATKEQSQV HLARGLPSMI DFQIS
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技术指标
Our Abpromise guarantee covers the use of ab9877 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Lyophilized -
补充说明
The ED50, determined by the dose-dependent stimulation of murine D10S cells, is < 0.005 ng/ml, corresponding to a specific activity of > 2 x 108 units/mg. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶For lot specific reconstitution information please contact our Scientific Support Team.
常规信息
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别名
- BAF
- FAF
- Hematopoietin 1
see all -
功能
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. -
序列相似性
Belongs to the IL-1 family. -
结构域
The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function. -
细胞定位
Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab9877 尚未被引用在任何文献中。
