重组小鼠Poliovirus Receptor/PVR蛋白(His tag) (Biotin) (ab271625)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组小鼠Poliovirus Receptor/PVR蛋白(His tag) (Biotin)
参阅全部 Poliovirus Receptor/PVR 蛋白酶 -
纯度
>= 90 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
序列
FCYALRKAGGDIRVLVPYNSTGVLGGSTTLHCSLTSNENVTITQITWMKK DSGGSHALVAVFHPKKGPNIKEPERVKFLAAQQDLRNASLAISNLSVEDE GIYECQIATFPRGSRSTNAWLKVQARPKNTAEALEPSPTLILQDVAKCIS ANGHPPGRISWPSNVNGSHREMKEPGSQPGTTTVTSYLSMVPSRQADGKN ITCTVEHESLQELDQLLVTLSQPYPPENVSISGYDGNWYVGLTNLTLTCE AHSKPAPDMAGYNWSTTTGDFPNSVKRQGNMLLISTVEDGLNNTVIVCEV TNALGSGQGQVHIIVKEKPENMQQNTRLHL -
预测分子量
38 kDa -
氨基酸
29 to 348 -
标签
His tag C-Terminus
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偶联物
Biotin
相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab271625 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
Enzymatically biotin-labeled using Avi-tag™ technology.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. Store In the Dark.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- CD155
- CD155 antigen
- FLJ25946
see all -
功能
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport. -
序列相似性
Belongs to the nectin family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
图片
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SDS-PAGE - Recombinant Mouse Poliovirus Receptor/PVR protein (His tag) (Biotin) (ab271625)
SDS-PAGE analysis of 3 µg ab271625.
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271625 尚未被引用在任何文献中。