重组小鼠PDE6C蛋白(Active) (ab271683)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 2% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组小鼠PDE6C蛋白(Active)
参阅全部 PDE6C 蛋白酶 -
生物活性
Specific Activity ≥ 600 pmol/min/µg.Unit Definition: One unit is defined as the amount of enzyme that will convert 1 pmole of 3′, 5′-cGMP to 5′-GMP per min at 37°C. -
纯度
>= 2 % SDS-PAGE.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
预测分子量
126 kDa -
氨基酸
2 to 861 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab271683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.31% Glutathione, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- 5''-cyclic phosphodiesterase subunit alpha''
- cGMP phosphodiesterase 6C
- COD4
see all -
疾病相关
Defects in PDE6C are the cause of cone dystrophy type 4 (COD4) [MIM:613093]. An early-onset cone dystrophy. Cone dystrophies are retinal dystrophies characterized by progressive degeneration of the cone photoreceptors with preservation of rod function, as indicated by electroretinogram. However, some rod involvement may be present in some cone dystrophies, particularly at late stage. Affected individuals suffer from photophobia, loss of visual acuity, color vision and central visual field. Another sign is the absence of macular lesions for many years. Cone dystrophies are distinguished from the cone-rod dystrophies in which some loss of peripheral vision also occurs. -
序列相似性
Belongs to the cyclic nucleotide phosphodiesterase family.
Contains 2 GAF domains. -
细胞定位
Cell membrane. - Information by UniProt
图片
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SDS-PAGE - Recombinant mouse PDE6C protein (Active) (ab271683)
Specific activity of ab271683 was ≥ 600 pmol/min/µg.
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SDS-PAGE - Recombinant mouse PDE6C protein (Active) (ab271683)SDS-PAGE analysis of ab271683.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271683 尚未被引用在任何文献中。