重组小鼠Ogg1蛋白(His tag) (ab222985)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS
描述
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产品名称
重组小鼠Ogg1蛋白(His tag)
参阅全部 Ogg1 蛋白酶 -
纯度
> 90 % SDS-PAGE.
ab222985 was purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
序列
MGSSHHHHHHSSGLVPRGSHMGSMLFRSWLPSSMRHRTLSSSPALWASIP CPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTEDQLYCTV YRGDDSQVSRPTLEELETLHKYFQLDVSLAQLYSHWASVDSHFQRVAQKF QGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVT YHGFPNLHALAGPEAETHLRKLGLGYRARYVRASAKAILEEQGGPAWLQQ LRVAPYEEAHKALCTLPGVGAKVADCICLMALDKPQAVPVDVHVWQIAHR DYGWHPKTSQAKGPSPLANKELGNFFRNLWGPYAGWAQAVLFSADLRQPS LSREPPAKRKKGSKRPEG -
预测分子量
41 kDa including tags -
氨基酸
1 to 345 -
标签
His tag N-Terminus -
额外的序列信息
NP_035087.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab222985 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Mass Spectrometry
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 30% Glycerol (glycerin, glycerine), PBS
常规信息
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别名
- 8 hydroxyguanine DNA glycosylase
- 8 oxoguanine DNA glycosylase
- 8 oxoguanine DNA glycosylase 1
see all -
功能
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. -
组织特异性
Ubiquitous. -
疾病相关
Defects in OGG1 may be a cause of renal cell carcinoma (RCC) [MIM:144700]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma. -
序列相似性
Belongs to the type-1 OGG1 family. -
细胞定位
Mitochondrion; Nucleus and Nucleus > nucleoplasm. Nucleus speckle. Nucleus matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. - Information by UniProt
图片
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SDS-PAGE - Recombinant Mouse Ogg1 protein (His tag) (ab222985)
15% SDS-PAGE analysis of 3 µg ab222985.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab222985 尚未被引用在任何文献中。