重组小鼠MALT1/MLT蛋白(Active) (ab271605)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 84% SDS-PAGE
- Active: Yes
- Tags: DDDDK tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies, WB
描述
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产品名称
重组小鼠MALT1/MLT蛋白(Active)
参阅全部 MALT1/MLT 蛋白酶 -
纯度
>= 84 % SDS-PAGE.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
预测分子量
93 kDa -
氨基酸
2 to 832 -
标签
DDDDK tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab271605 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 20% Glycerol (glycerin, glycerine)
100ng/ul DDDDK peptideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- Caspase like protein
- DKFZp434L132
- IMD12
see all -
功能
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. -
组织特异性
Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung. -
疾病相关
Note=A chromosomal aberration involving MALT1 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with BIRC2. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma. -
序列相似性
Belongs to the peptidase C14B family.
Contains 1 death domain.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
细胞定位
Cytoplasm > perinuclear region. Nucleus. Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10. - Information by UniProt
图片
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Functional Studies - Recombinant mouse MALT1/MLT protein (Active) (ab271605)Specific activity of ab271605.
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Western blot - Recombinant mouse MALT1/MLT protein (Active) (ab271605)Recombinant mouse MALT1/MLT protein (Active) (ab271605) used as a positive control in WB.
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SDS-PAGE - Recombinant mouse MALT1/MLT protein (Active) (ab271605)SDS-PAGE analysis of 3 µg ab271605.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271605 尚未被引用在任何文献中。