重组小鼠GRHPR蛋白(Tagged) (ab226316)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组小鼠GRHPR蛋白(Tagged)
参阅全部 GRHPR 蛋白酶 -
纯度
> 90 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
序列
MKPARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVV GAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRV GYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLWMCGYG LSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAEFQAEFV PIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVN QEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYK TRNTMSLLAANNLLAGLRGEAMPSELKL -
预测分子量
51 kDa including tags -
氨基酸
1 to 328 -
标签
His tag N-Terminus -
额外的序列信息
N-terminal 6xHis-SUMO tag.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab226316 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: 50% Glycerol (glycerin, glycerine), Tris buffer
常规信息
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别名
- GLXR
- glycerate 2 dehydrogenase
- GLYD
see all -
功能
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate. -
组织特异性
Ubiquitous. Most abundantly expressed in the liver. -
疾病相关
Defects in GRHPR are the cause of hyperoxaluria primary type 2 (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L-glycerate. -
序列相似性
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. - Information by UniProt
图片
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SDS-PAGE - Recombinant Mouse GRHPR protein (Tagged) (ab226316)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab226316 尚未被引用在任何文献中。