重组小鼠Fibroblast activation蛋白，alpha (Tagged) (ab271506)
Key features and details
- Expression system: HEK 293 cells
- Purity: = 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组小鼠Fibroblast activation蛋白，alpha (Tagged)
参阅全部 Fibroblast activation protein, alpha 蛋白酶 -
纯度
= 90 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
序列
LRPSRVYKPE GNTKRALTLK DILNGTFSYK TYFPNWISEQ EYLHQSEDDN IVFYNIETRE SYIILSNSTM KSVNATDYGL SPDRQFVYLE SDYSKLWRYS YTATYYIYDL QNGEFVRGYE LPRPIQYLCW SPVGSKLAYV YQNNIYLKQR PGDPPFQITY TGRENRIFNG IPDWVYEEEM LATKYALWWS PDGKFLAYVE FNDSDIPIIA YSYYGDGQYP RTINIPYPKA GAKNPVVRVF IVDTTYPHHV GPMEVPVPEM IASSDYYFSW LTWVSSERVC LQWLKRVQNV SVLSICDFRE DWHAWECPKN QEHVEESRTG WAGGFFVSTP AFSQDATSYY KIFSDKDGYK HIHYIKDTVE NAIQITSGKW EAIYIFRVTQ DSLFYSSNEF EGYPGRRNIY RISIGNSPPS KKCVTCHLRK ERCQYYTASF SYKAKYYALV CYGPGLPIST LHDGRTDQEI QVLEENKELE NSLRNIQLPK VEIKKLKDGG LTFWYKMILP PQFDRSKKYP LLIQVYGGPC SQSVKSVFAV NWITYLASKE GIVIALVDGR GTAFQGDKFL HAVYRKLGVY EVEDQLTAVR KFIEMGFIDE ERIAIWGWSY GGYVSSLALA SGTGLFKCGI AVAPVSSWEY YASIYSERFM GLPTKDDNLE HYKNSTVMAR AEYFRNVDYL LIHGTADDNV HFQNSAQIAK ALVNAQVDFQ AMWYSDQNHG ISSGRSQNHL YTHMTHFLKQ CFSLSD -
预测分子量
88 kDa including tags -
氨基酸
26 to 761 -
标签
His tag C-Terminus -
额外的序列信息
Genbank: NM_007986
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技术指标
Our Abpromise guarantee covers the use of ab271506 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 1.61% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- 170 kDa melanoma membrane bound gelatinase
- 170 kDa melanoma membrane-bound gelatinase
- DPPIV
see all -
功能
In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. -
组织特异性
Fibroblast specific. -
序列相似性
Belongs to the peptidase S9B family. -
翻译后修饰
N-glycosylated.
The N-terminus may be blocked. -
细胞定位
Cell membrane. Cell projection > lamellipodium membrane. Cell projection > invadopodium membrane. Found in cell surface lamellipodia, invadopodia and on shed vesicles. Colocalized with DPP4 in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with DPP4 on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma. - Information by UniProt
图片
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SDS-PAGE - Recombinant Mouse Fibroblast activation protein, alpha (Tagged) (ab271506)
SDS-PAGE by analysis of ab271506.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271506 尚未被引用在任何文献中。