重组小鼠CD105蛋白(ab54339)
Key features and details
- Expression system: Insect cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, ELISA
描述
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产品名称
重组小鼠CD105蛋白
参阅全部 CD105 蛋白酶 -
纯度
> 95 % SDS-PAGE.
Purity: > 95% (SDS-PAGE and visualized by Silverstain). Endotoxin level: < 0.1 ng per µg of CD105. Affinity purified. -
表达系统
Insect cells -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
氨基酸
1 to 581
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab54339 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
ELISA
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶The protein can also be reconstituted in ddH2O or PBS to a concentration of 100µg/ml. The carrier-free protein should be used immediately upon reconstitution to avoid losses in activity due to non-specific binding to the inside surface of the vial. For long term storage as a dilute solution, a carrier protein (e.g. 0.1% HSA or BSA) should be added to the vial.
常规信息
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别名
- AI528660
- AI662476
- CD 105
see all -
功能
Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. -
组织特异性
Endoglin is restricted to endothelial cells in all tissues except bone marrow. -
疾病相关
Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. -
细胞定位
Membrane. - Information by UniProt
图片
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SDS-PAGE analysis of recombinant mouse soluble CD105 from insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing conditions and stained with Silver stain.
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ab54339 on SDS-PAGE
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
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