重组人/小鼠TGF beta 3蛋白(Animal Free) (ab179495)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: <= 1.000 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
-
产品名称
重组人/小鼠TGF beta 3蛋白(Animal Free)
参阅全部 TGF beta 3 蛋白酶 -
生物活性
The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than
0.05 ng/mL.
-
纯度
> 95 % SDS-PAGE.
Purity (typically >/= 98%) determined by Reducing and Non-reducing SDS-PAGE. ab179495 is sterile filtered. -
内毒素水平
<=1.000 Eu/µg -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
Yes -
性质
Recombinant -
-
种属
Human -
序列
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS -
预测分子量
26 kDa -
氨基酸
301 to 412 -
额外的序列信息
Non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains.
-
-
描述
重组人TGF beta 3蛋白(Animal Free)
技术指标
Our Abpromise guarantee covers the use of ab179495 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Functional Studies
SDS-PAGE
-
形式
Liquid -
补充说明
This product is produced with no animal-derived raw products, animal free equipment and animal free protocols.
This product shares 100% homology with amino acids 299 - 410 Mouse TGF beta 3.
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C.
Constituents: 20% Ethanol, 0.06% Acetic acid
This product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
-
别名
- ARVD
- ARVD1
- FLJ16571
see all -
功能
Involved in embryogenesis and cell differentiation. -
疾病相关
Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. -
序列相似性
Belongs to the TGF-beta family. -
细胞定位
Secreted. - Information by UniProt
图片
-
Functional Studies - Recombinant human/mouse TGF beta 3 protein (Animal Free) (ab179495)Functional analysis of ab179495
-
SDS-PAGE - Recombinant human/mouse TGF beta 3 protein (Animal Free) (ab179495)SDS PAGE analysis of ab179495 under non-reducing (-) and reducing (+) conditions. Stained with Coomassie Blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab179495 尚未被引用在任何文献中。