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AB165455

重组人 ZNF358 蛋白 (GST tag N-Terminus)

Recombinant Human ZNF358 protein (GST tag N-Terminus)

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Recombinant Human ZNF358 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 481 aa range, expressed in Wheat germ, suitable for ELISA, WB.

查看别名

Zinc finger protein 358, ZNF358

1 Images
SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)

ab165455 on a 12.5% SDS-PAGE stained with Coomassie Blue.

关键信息

表达系统

Wheat germ

标签

GST tag N-Terminus

应用

WB, ELISA

applications

生物活性

No

访问

Q9NW07

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"sequence":"MSSSFDLDPDVIGPVPLILDPNSDTLSPGDPKVDPISSGLTATPQVLATSPAVLPAPASPPRPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACGKAFGWRSTLLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESPEWVQEQGALLGPDG","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":481,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NW07","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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性能和储存信息

运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZNF358 also known as ZFP358 is a zinc finger protein playing a role in gene transcription regulation. It has a molecular mass of approximately 85 kDa. This protein is known to bind DNA in a sequence-specific manner using the zinc finger motifs to function as a transcription factor. ZNF358 expression occurs in multiple tissues with research indicating significant levels in the brain and heart. The protein's mechanical action involves modulating the transcription of specific genes impacting various biological processes.
Biological function summary

ZNF358 modulates critical processes in cellular differentiation and development. As a member of the transcription factor family ZNF358 does not form part of a known multi-protein complex. Instead it functions independently influencing the transcription of genes involved in cellular responses and structural development. This protein plays a role in maintaining cellular homeostasis affecting developmental stages by activating or repressing target gene transcription.

Pathways

ZNF358 influences several notably the Wnt signaling pathway and the Notch signaling pathway. In the Wnt signaling pathway ZNF358 interacts with proteins involved in cellular growth and differentiation such as β-catenin. This pathway plays a significant role in embryonic development and tissue regeneration. In relation to Notch signaling ZNF358 interacts with pathway components influencing cell fate determination and neural development collaborating with proteins like Notch receptors.

ZNF358 shows associations with developmental disorders particularly related to neural and cardiac malformations. Aberrant expression or dysfunction of ZNF358 may contribute to conditions like congenital heart defects due to its impact on cardiac development genes. Additionally disrupted ZNF358 function has links to neurodevelopmental disorders influencing neural pathway genes. Any interactions leading to disease often involve other transcription factors that interact with this protein in the developmental pathways.
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特殊说明

形式

Liquid

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常规信息

功能

May be involved in transcriptional regulation.

序列相似性

Belongs to the krueppel C2H2-type zinc-finger protein family.

亚细胞定位

Nucleus

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产品实验方案

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靶点信息

May be involved in transcriptional regulation.
See full target information ZNF358
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