JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB181934

重组人 ZNF32 蛋白 (denatured) (His tag N-Terminus)

Recombinant Human ZNF32 protein (denatured) (His tag N-Terminus)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human ZNF32 protein (denatured) (His tag N-Terminus) is a Human Full Length protein, in the 1 to 273 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

查看别名

KOX30, ZNF32, Zinc finger protein 32, C2H2-546, Zinc finger protein KOX30

1 Images
SDS-PAGE - Recombinant Human ZNF32 protein (denatured) (His tag N-Terminus) (AB181934)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ZNF32 protein (denatured) (His tag N-Terminus) (AB181934)

15% SDS-PAGE analysis of 3 μg ab181934.

关键信息

纯度

>85% SDS-PAGE

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

SDS-PAGE

applications

生物活性

No

访问

P17041

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMFGFPTATLLDCHGRYAQNVAFFNVMTEAHHKYDHSEATGSSSWDIQNSFRREKLEQKSPDSKTLQEDSPGVRQRVYECQECGKSFRQKGSLTLHERIHTGQKPFECTHCGKSFRAKGNLVTHQRIHTGEKPYQCKECGKSFSQRGSLAVHERLHTGQKPYECAICQRSFRNQSNLAVHRRVHSGEKPYRCDQCGKAFSQKGSLIVHIRVHTGLKPYACTQCRKSFHTRGNCILHGKIHTGETPYLCGQCGKSFTQRGSLAVHQRSCSQRLTL","proteinLength":"Full Length","predictedMolecularWeight":"33.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":273,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P17041","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

性能和储存信息

运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZNF32 also known as Zinc Finger Protein 32 acts mechanically as a transcription factor. This protein with a molecular mass around 59 kDa binds to specific DNA sequences influencing gene expression. Researchers have identified its robust expression in several tissues including the brain liver and spleen. ZNF32 plays a role in gene regulation and its zinc finger motifs allow it to interact with DNA enabling transcriptional regulation functions.
Biological function summary

ZNF32 regulates the expression of various genes involved in cell survival and apoptosis. It does not form part of a known complex but its activity influences important cellular processes. This regulatory capacity impacts cellular responses to stress and contributes to homeostasis within different cellular environments. Its ability to modulate gene expression links it to the control of cell proliferation and differentiation.

Pathways

ZNF32 becomes important in the apoptosis and cell cycle regulation pathways. It interacts with other transcription factors and proteins like p53 in apoptosis signaling pathways. This involvement in the recycling of cellular components places ZNF32 in direct relation with multiple signaling cascades that sustain cellular function and survival. These interactions highlight its necessity in maintaining cellular integrity and preventing unwanted cell death.

ZNF32 shows association with cancer and neurodegenerative disorders. Aberrant expression or mutations in the ZNF32 gene may correlate with increased tumorigenesis largely through its interaction with p53 during apoptosis. ZNF32 also demonstrates a connection to Alzheimer's disease likely influencing pathways with associated proteins like tau. Understanding these interactions aids in recognizing how ZNF32 modifications can contribute to pathology.

特殊说明

形式

Liquid

常规信息

功能

May be involved in transcriptional regulation.

序列相似性

Belongs to the krueppel C2H2-type zinc-finger protein family.

亚细胞定位

Nucleus

产品实验方案

靶点信息

May be involved in transcriptional regulation.
See full target information ZNF32

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂,为您科研的每一步提供支持。若我们的产品未能达到预期性能,我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com