重组人 ZCCHC12 蛋白 (denatured) (His tag N-Terminus)
Recombinant Human ZCCHC12 protein (denatured) (His tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human ZCCHC12 protein (denatured) (His tag N-Terminus) is a Human Full Length protein, in the 1 to 402 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
查看别名
SIZN1, ZCCHC12, Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ZCCHC12 protein (denatured) (His tag N-Terminus) (AB181905)
15% SDS-PAGE analysis of 3ug ab181905 stained with Coomassie Blue.
反应性数据
序列信息
性能和储存信息
形式
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ZCCHC12 influences gene expression by participating in RNA processing activities. It is not known to be part of a larger complex but acts independently to modulate the stability and translation of specific mRNA transcripts. Research indicates its involvement in maintaining neuronal homeostasis as it directly influences synaptic function and plasticity. The protein's role in regulating neuronal gene expression is important for normal central nervous system function.
Pathways
The protein interacts with molecular mechanisms such as the JAK-STAT signaling pathway and the mTOR pathway both important for cellular growth and immune response. Within these pathways ZCCHC12 often interacts with proteins like STAT3 and mTOR which play roles in cell proliferation and metabolism. These interactions underline its importance in maintaining cellular architecture and functional dynamics.
常规信息
功能
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).
序列相似性
Belongs to the ZCCHC12 family.
靶点信息
Abcam Product Promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com