JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB276613

重组人VPAC2蛋白(Fc Chimera)

Recombinant Human VPAC2 protein (Fc Chimera)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human VPAC2 protein (Fc Chimera) is a Human Fragment protein, in the 1 to 126 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

查看别名

VIP2R, VIPR2, Vasoactive intestinal polypeptide receptor 2, VIP-R-2, Helodermin-preferring VIP receptor, Pituitary adenylate cyclase-activating polypeptide type III receptor, VPAC2 receptor, PACAP type III receptor, PACAP-R-3, PACAP-R3, VPAC2R

1 Images
SDS-PAGE - Recombinant Human VPAC2 protein (Fc Chimera) (AB276613)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human VPAC2 protein (Fc Chimera) (AB276613)

SDS-PAGE analysis of ab276613.

The apparent molecular mass of the monomer is approximately 50.6 kDa in SDS-PAGE under reducing conditions.

关键信息

纯度

>90% SDS-PAGE

内毒素水平

< 1 EU/µg

表达系统

HEK 293 cells

标签

Fc tag C-Terminus

应用

SDS-PAGE

applications

生物活性

No

访问

P41587

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 7.4 Constituents: PBS

storage-buffer

style
left-column

搭配使用产品

Primary Antibodies

AB28624

Anti-VPAC2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VPAC2 antibody (AB28624)

  • 4
  • 2
style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>The apparent molecular mass of the monomer is approximately 50.6 kDa in SDS-PAGE under reducing conditions.</p>" } } }
style
left-column
style
left-column

序列信息

[{"linker":null,"sequence":"MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILV","proteinLength":"Fragment","predictedMolecularWeight":"38.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":126,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P41587","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]
style
left-column

性能和储存信息

形式
Lyophilized
运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

常规信息

功能

G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of potency PACAP38 = VIP > PACAP27 (PubMed : 35477937, PubMed : 8933357). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). May be coupled to phospholipase C.

序列相似性

Belongs to the G-protein coupled receptor 2 family.

style
left-column

产品实验方案

style
left-column

靶点信息

G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of potency PACAP38 = VIP > PACAP27 (PubMed : 35477937, PubMed : 8933357). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). May be coupled to phospholipase C.
See full target information VIPR2
style
left-column
style
left-column
style
right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com