AB217407

重组人Vitronectin/S-Protein (Animal Free)

Name: 重组人Vitronectin/S-Protein (Animal Free) (ab217407)| Abcam中文官网
Brand: Abcam Limited
SKU: AB217407
Price: 1650 CNY
Availability: InStock

Recombinant human Vitronectin/S-Protein (Animal Free)

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(1 Publication)

Recombinant human Vitronectin/S-Protein (Animal Free) is a Human Full Length protein, in the 20 to 478 aa range, expressed in HEK 293 cells, with >95%, suitable for SDS-PAGE, FuncS, HPLC.

查看别名

Vitronectin, VN, S-protein, Serum-spreading factor, V75, VTN

关键信息

纯度

>95% SDS-PAGE

表达系统

HEK 293 cells

应用

SDS-PAGE, FuncS, HPLC

applications

生物活性

Yes

生物学活性

Recombinant human Vitronectin promotes attachment of hESC and iPSC in serum-free, feeder conditionsat 5ug/ml.

访问

P04004

不含动物源

Yes

不含载体蛋白

种属

Human

复溶

Reconstitute in water

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" } } }

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序列信息

[{"sequence":"DQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL","proteinLength":"Full Length","predictedMolecularWeight":"52.29 kDa","actualMolecularWeight":null,"aminoAcidEnd":478,"aminoAcidStart":20,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P04004","tags":[]}]

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性能和储存信息

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

True

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特殊说明

形式

Lyophilized

附加说明

>95% by HPLC.

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常规信息

功能

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

翻译后修饰

Sulfated on tyrosine residues.. N- and O-glycosylated.. Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.. It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.. Phosphorylation sites are present in the extracellular medium.

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产品实验方案

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information Vitronectin

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cell biology international : PubMed38654431

2024

Vitronectin promotes insulin resistance in trophoblast cells by activating JNK in gestational diabetes mellitus.

Applications

Unspecified application

Species

Unspecified reactive species

Yuejun Ju,Ting Shen,Zhanhong Guo,Yinghong Kong,Yun Huang,Ji Hu

View all publications

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重组人Vitronectin/S-Protein (Animal Free)

Recombinant human Vitronectin/S-Protein (Animal Free)

关键信息

纯度

表达系统

标签

应用

生物活性

生物学活性

访问

不含动物源

不含载体蛋白

种属

复溶