重组人Vitronectin/S-Protein
Recombinant Human Vitronectin/S-Protein
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Recombinant Human Vitronectin/S-Protein is a Human Full Length protein, in the 20 to 478 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, HPLC.
查看别名
Vitronectin, VN, S-protein, Serum-spreading factor, V75, VTN
反应性数据
产品详情
序列信息
性能和储存信息
运输条件
推荐的短期储存条件
推荐的长期储存条件
特殊说明
形式
Lyophilized
附加说明
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Lyophilized from a 0.2 µM filtered solution
常规信息
功能
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
翻译后修饰
Sulfated on tyrosine residues.. N- and O-glycosylated.. Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.. It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.. Phosphorylation sites are present in the extracellular medium.
靶点信息
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