重组人Vav蛋白(ab172184)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 70% Densitometry
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, WB
描述
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产品名称
重组人Vav蛋白 -
纯度
> 70 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
PFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDL MRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRF LKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERF LVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLM VPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDN ETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLL DKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQ GAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETT SCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKK DKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVEL TKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPME RAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLY RITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPA VGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYG RVGWFPANYVEEDYSEYC -
预测分子量
120 kDa including tags -
氨基酸
73 to 845 -
标签
GST tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab172184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.50
Constituents: 73% Tris-HCl buffer, 25% Glycerol (glycerin, glycerine), 0.29% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF
常规信息
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别名
- 2810040F13Rik
- A530094I06Rik
- AA986410
see all -
相关性
The Vav family are Rho/Rac guanosine nucleotide exchange factors (GEFs), consisting of three members in mammalian cells (Vav, Vav2, Vav3) and one in nematodes (CelVav). First discovered based on its transforming properties, Vav is expressed mainly in hematopoietic cells and a few non-hematopoietic tissues, such as the pancreas and tooth enamels. As a signalling transducer, Vav is involved in T-cell activated transduction of T-cell antigen receptor (TCR). T-cell stimulated and tyrosine phosphorylated Vav acts as a catalyst in the exchange of guanosine nucleotides on Rac-1, a GTP binding protein. Using a mouse model, Vav expression has been determined to play an essential role in the cyctosketetal, proliferative, and apoptotic pathways for developing lymphoid cells and its signal response. -
细胞定位
Cytoplasmic and Plasma membrane VAV1, Cytoplasm - VAV2 & VAV3
图片
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SDS-PAGE - Recombinant Human Vav proteins (ab172184)
ab172184 on SDS-PAGE, MW ~120 kDa.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab172184 尚未被引用在任何文献中。