重组人USP3蛋白(ab127142)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His-DHFR tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人USP3蛋白 -
纯度
> 85 % SDS-PAGE.
Purified via His tag -
表达系统
Escherichia coli -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
24 kDa -
氨基酸
313 to 520 -
标签
His-DHFR tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab127142 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20ºC.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
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复溶Reconstitute with water to desired concentration.
常规信息
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别名
- Deubiquitinating enzyme 3
- EC 3.1.2.15
- SIH003
see all -
功能
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. -
组织特异性
Expressed in all tissues examined, with strongest expression in pancreas. -
序列相似性
Belongs to the peptidase C19 family. USP3 subfamily.
Contains 1 UBP-type zinc finger. -
结构域
Both protease activity and an intact zinc finger are required for H2A monodeubiquitination. -
细胞定位
Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab127142 尚未被引用在任何文献中。
