重组人TNFRSF14/HVEM蛋白(Active) (ab271546)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: Fc tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人TNFRSF14/HVEM蛋白(Active)
参阅全部 TNFRSF14/HVEM 蛋白酶 -
生物活性
Active in a BTLA:TNFRSF14/HVEM binding assay.
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纯度
>= 90 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
PALPSCKEDE YPVGSECCPK CSPGYRVKEA CGELTGTVCE PCPPGTYIAH LNGLSKCLQC QMCDPAMGLR ASRNCSRTEN AVCGCSPGHF CIVQDGDHCA ACRAYATSSP GQRVQKGGTE SQDTLCQNCP PGTFSPNGTL EECQHQTKCS WLVTKAGAGT SSSHWV -
预测分子量
44 kDa including tags -
分子量信息
Protein runs at higher than predicted MW on SDS-PAGE due to glycosylation. -
氨基酸
37 to 202 -
标签
Fc tag C-Terminus -
额外的序列信息
Human IgG1 Fc. Genbank: NM_003820
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技术指标
Our Abpromise guarantee covers the use of ab271546 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- HVEML
- ATAR
- CD270
see all -
功能
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. -
组织特异性
Widely expressed, with the highest expression in lung, spleen and thymus. -
序列相似性
Contains 3 TNFR-Cys repeats. -
翻译后修饰
N-glycosylated. -
细胞定位
Membrane. - Information by UniProt
图片
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Functional Studies - Recombinant human TNFRSF14/HVEM protein (Active) (ab271546)
Functional analysis of ab271546.
Active in a BTLA:TNFRSF14/HVEM binding assay.
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SDS-PAGE - Recombinant Human TNFRSF14/HVEM protein (Tagged) (ab271546)SDS-PAGE analysis of ab271546.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271546 尚未被引用在任何文献中。