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AB167711

Recombinant human TFPI protein

Recombinant human TFPI protein

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Recombinant human TFPI protein is a Human Fragment protein, in the 29 to 282 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

查看别名

LACI, TFPI1, TFPI, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, EPI

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SDS-PAGE - Recombinant human TFPI protein (AB167711)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human TFPI protein (AB167711)

Human TFPI (His Tag) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

SDS-PAGE - Recombinant human TFPI protein (AB167711)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human TFPI protein (AB167711)

SDS-PAGE of reduced ab167711 stained overnight with Coomassie Blue.

关键信息

纯度

>90% SDS-PAGE

内毒素水平

< 1 EU/µg

表达系统

HEK 293 cells

标签

His tag C-Terminus

应用

SDS-PAGE, FuncS

applications

生物活性

Yes

生物学活性

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca - RPKPVE - Nval– WRK(Dnp) - NH2.The IC50 value is < 0.35 nM, as measured in 100 μl reaction mixture containing 1.25 ng trypsin, 10 μM substrate, 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% Brij-35 (w/v), pH 7.5.

访问

P10646

不含动物源

No

不含载体蛋白

No

种属

Human

复溶

Reconstitute the lyophilized protein in sterile deionized water to a final concentration of 400 ug/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

存储溶液

pH: 7.4 Constituents: 95% PBS, 5% Trehalose

storage-buffer

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>DTT-reduced Protein migrates as 41-45 kDa due to glycosylation</p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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为什么推荐这个？

我们推荐这个产品，因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书，以确认其是否符合您的实验需求；若有疑问，也可联系我们的技术团队获取协助。

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序列信息

[{"sequence":"DSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIK","proteinLength":"Fragment","predictedMolecularWeight":"30 kDa","actualMolecularWeight":null,"aminoAcidEnd":282,"aminoAcidStart":29,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P10646","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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性能和储存信息

运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-80°C
储存信息
Avoid freeze / thaw cycle
True
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特殊说明

形式

Lyophilized

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常规信息

功能

Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

翻译后修饰

O-glycosylated.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
See full target information TFPI
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详情请参阅我们的条款与条件。
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