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重组人SMAD5蛋白(ab84651)

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SDS-PAGE - Recombinant Human SMAD5 protein (ab84651)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 85% Densitometry
    • Suitable for: WB, SDS-PAGE

    描述

    • 产品名称

      重组人SMAD5蛋白

    • 纯度

      > 85 % Densitometry.

    • 表达系统

      Escherichia coli

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

    技术指标

    Our Abpromise guarantee covers the use of ab84651 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      Western blot

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 7.50
      Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

    常规信息

    • 别名

      • DKFZp781C1895
      • DKFZp781O1323
      • Dwfc
      • hSmad5
      • JV5 1
      • JV5-1
      • MAD homolog 5
      • MAD, mothers against decapentaplegic homolog 5
      • MADH 5
      • MADH5
      • Mothers against decapentaplegic homolog 5
      • mothers against decapentaplegic, drosophila, homolog of, 5
      • Mothers against DPP homolog 5
      • MusMLP
      • SMA and MAD related protein 5
      • SMAD 5
      • SMAD family member 5
      • SMAD, mothers against DPP homolog 5
      • Smad5
      • SMAD5_HUMAN
      see all

    • 功能

      Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

    • 组织特异性

      Ubiquitous.

    • 序列相似性

      Belongs to the dwarfin/SMAD family.
      Contains 1 MH1 (MAD homology 1) domain.
      Contains 1 MH2 (MAD homology 2) domain.

    • 翻译后修饰

      Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
      Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.

    • 细胞定位

      Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human SMAD5 protein (ab84651)
      SDS-PAGE - Recombinant Human SMAD5 protein (ab84651)
      SDS-PAGE showing ab84651 at approximately 82kDa.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab84651？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab84651 尚未被引用在任何文献中。

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