重组人SLAM / CD150蛋白(Tagged) (Biotin) (ab271408)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人SLAM / CD150蛋白(Tagged) (Biotin)
参阅全部 SLAM / CD150 蛋白酶 -
纯度
>= 90 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
ASYGTGGRMM NCPKILRQLG SKVLLPLTYE RINKSMNKSI HIVVTMAKSL ENSVENKIVS LDPSEAGPPR YLGDRYKFYL ENLTLGIRES RKEDEGWYLM TLEKNVSVQR FCLQLRLYEQ VSTPEIKVLN KTQENGTCTL ILGCTVEKGD HVAYSWSEKA GTHPLNPANS SHLLSLTLGP QHADNIYICT VSNPISNNSQ TFSPWPGCRT DPSETKP -
预测分子量
53 kDa including tags -
分子量信息
Proteins at higher MW than predicted on SDS-PAGE due to glycosylation. -
氨基酸
21 to 237 -
标签
Avi tag C-Terminus , Fc tag C-Terminus -
额外的序列信息
Fc region of human IgG1. Genbank: NM_003037
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偶联物
Biotin
技术指标
Our Abpromise guarantee covers the use of ab271408 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
Enzymatically biotin-labeled using Avi-tag™ technology
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. Store In the Dark.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- 4933415F16
- AA177906
- CD 150
see all -
功能
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. -
组织特异性
Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. -
序列相似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
结构域
The most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues. -
翻译后修饰
Phosphorylated by FYN. -
细胞定位
Cell membrane. Present on the surface of B-cells and T-cells. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human SLAM / CD150 protein (Tagged) (Biotin) (ab271408)SDS-PAGE analysis of ab271408.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271408 尚未被引用在任何文献中。