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重组人SIT蛋白(ab113580)

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SDS-PAGE - Recombinant Human SIT protein (ab113580)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: MS, SDS-PAGE

    描述

    • 产品名称

      重组人SIT蛋白
      参阅全部 SIT 蛋白酶

    • 纯度

      > 90 % SDS-PAGE.
      ab113580 is purified using conventional chromatography techniques.

    • 表达系统

      Escherichia coli

    • Accession

      Q9Y3P8

    • 蛋白长度

      Protein fragment

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MGSSHHHHHHSSGLVPRGSHMHLSQWTRGRSRSHPGQGRSGESVEEVPLY GNLHYLQTGRLSQDPEPDQQDPTLGGPARAAEEVMCYTSLQLRPPQGRIP GPGTPVKYSEVVLDSEPKSQASGPEPELYASVCAQTRRARASFPDQAYAN SQPAAS

      • 预测分子量

        17 kDa including tags

      • 氨基酸

        62 to 196

      • 标签

        His tag N-Terminus

    技术指标

    Our Abpromise guarantee covers the use of ab113580 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      Mass Spectrometry

      SDS-PAGE

    • 质谱法

      MALDI-TOF

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine)

    常规信息

    • 别名

      • gp30/40
      • SHP intracting transmembrane adapter protein
      • SHP2-interacting transmembrane adapter protein
      • Signaling threshold-regulating transmembrane adapter 1
      • SIT
      • Sit1
      • SIT1_HUMAN
      • Suppression inducing transmembrane adapter 1
      • Suppression-inducing transmembrane adapter 1
      see all

    • 功能

      Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.

    • 组织特异性

      Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma.

    • 翻译后修饰

      Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation; which leads to the recruitment of PTPN11, GRB2 and CSK.

    • 细胞定位

      Cell membrane.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human SIT protein (ab113580)
      SDS-PAGE - Recombinant Human SIT protein (ab113580)
      15% SDS-PAGE showing ab113580 (3µg).

      Note: Molecular weight on SDS-PAGE will appear higher.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab113580？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab113580 尚未被引用在任何文献中。

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