重组人SHP1蛋白(ab61135)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组人SHP1蛋白
参阅全部 SHP1 蛋白酶 -
纯度
> 90 % Densitometry. -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
标签
GST tag N-Terminus
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相关产品
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Affibody® Molecule
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab61135 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.418% MOPS, 0.00174% PMSF, 0.00385% DTT, 30% Glycerol (glycerin, glycerine), 50% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- 70Z-SHP
- EC 3.1.3.48
- HCP
see all -
功能
Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. -
组织特异性
Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells. -
序列相似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Contains 2 SH2 domains.
Contains 1 tyrosine-protein phosphatase domain. -
翻译后修饰
Phosphorylated on serine and tyrosine residues. -
细胞定位
Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II. - Information by UniProt
图片
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Functional Studies - Recombinant human SHP1 protein (ab61135)The specific activity of SHP1 (ab61135) was determined to be 1100 nmol phosphate released/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human SHP1 protein (ab61135)SDS PAGE analysis of ab61135 -
SDS-PAGE - Recombinant human SHP1 protein (ab61135)SDS PAGE analysis of ab61135 -
Functional Studies - Recombinant human SHP1 protein (ab61135)Sample Kinase Activity Plot. -
SDS-PAGE - Recombinant human SHP1 protein (ab61135)ab61135 on SDS-PAGE, MW ~93 kDa.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab61135 尚未被引用在任何文献中。