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AB276605

重组人SEZ6L2蛋白(His tag)

Recombinant Human SEZ6L2 protein (His tag)

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Recombinant Human SEZ6L2 protein (His tag) is a Human Fragment protein, in the 1 to 736 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

查看别名

PSK, UNQ1903/PRO4349, SEZ6L2, Seizure 6-like protein 2

1 Images
SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)

SDS-PAGE analysis of ab276605.

关键信息

纯度

>95% SDS-PAGE

内毒素水平

< 1 EU/µg

表达系统

HEK 293 cells

标签

His tag C-Terminus

应用

SDS-PAGE

applications

生物活性

No

访问

Q6UXD5

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 7.4 Constituents: PBS

storage-buffer

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搭配使用产品

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

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Proteins & Peptides

AB158403

Recombinant Human Factor VIII protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Factor VIII protein (GST tag N-Terminus) (AB158403)

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Proteins & Peptides

AB161580

Recombinant Human SCC112 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human SCC112 protein (GST tag N-Terminus) (AB161580)

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  • 0
Primary Antibodies

AB108403

Anti-CD38 antibody [EPR4106]

20ul selling size|RabMAb|KO Validated|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD38 antibody [EPR4106] (AB108403)

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Proteins & Peptides

AB132656

Recombinant Human OAS2 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human OAS2 protein (GST tag N-Terminus) (AB132656)

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  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"MGTPRAQHPPPPQLLFLILLSCPWIQGLPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGPEGGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS","proteinLength":"Fragment","predictedMolecularWeight":"77.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":736,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6UXD5","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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性能和储存信息

形式
Lyophilized
运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

SEZ6L2 also known as Seizure 6-like protein 2 is a transmembrane protein with an approximate mass of 100 kDa. This protein contains several domains including CUB and Sushi/SCR/CCP domains which suggest roles in cell signal recognition and interaction. SEZ6L2 expresses mainly in the brain with a concentration in regions such as the cerebral cortex and hippocampus implicating it within processes critical to neurological development and function.
Biological function summary

SEZ6L2 has important roles in synaptic transmission and plasticity. It is part of a larger complex that influences the development and maintenance of synapses. Current research suggests that SEZ6L2 affects the signaling pathways in neurons and may involve the modulation of synaptic strength impacting cognitive functions such as learning and memory.

Pathways

SEZ6L2 is involved in the regulation of synaptic signaling pathways. It interacts significantly with proteins in the cAMP signaling pathway which is important for translating extracellular signals into cellular responses and neurotrophic pathway which involves proteins like BDNF. These pathways are essential for cellular survival differentiation and plasticity in neural cells further linking SEZ6L2 to neurological processes.

SEZ6L2 has associations with several neurological conditions including epilepsy and autism spectrum disorders. In epilepsy SEZ6L2 interacts with other seizure-related proteins that affect neuronal excitability and network stability. For autism spectrum disorders changes in SEZ6L2 expression or function likely alter synaptic connectivity and signal transmission influencing behavioral and cognitive symptoms associated with this disorder.
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常规信息

功能

May contribute to specialized endoplasmic reticulum functions in neurons.

序列相似性

Belongs to the SEZ6 family.

翻译后修饰

O-glycosylated with core 1 or possibly core 8 glycans.

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产品实验方案

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靶点信息

May contribute to specialized endoplasmic reticulum functions in neurons.
See full target information SEZ6L2
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