重组人ROS1蛋白(ab125624)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 75% Densitometry
- Active: Yes
- Suitable for: WB, Functional Studies, SDS-PAGE
描述
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产品名称
重组人ROS1蛋白
参阅全部 ROS1 蛋白酶 -
生物活性
The specific activity of ab125624 was determined to be 640 nmol/min/mg.
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纯度
> 75 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
82 kDa including tags -
氨基酸
1883 to 2347
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab125624 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
Functional Studies
SDS-PAGE
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形式
Liquid -
补充说明
ab204862 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.003% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- c ros
- c ros 1
- c ros oncogene 1 receptor tyrosine kinase
see all -
功能
This is probably a cell growth or differentiation factor receptor with a tyrosine-protein kinase activity. -
组织特异性
Expressed in brain. Expression is increased in primary gliomas. -
疾病相关
Note=A chromosomal aberration involving ROS1 is found in a glioblastoma multiforme sample. An intra-chromosomal deletion del(6)(q21q21) is responsible for the formation of GOPC-ROS1 chimeric protein which has a constitutive receptor tyrosine kinase activity. -
序列相似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Contains 9 fibronectin type-III domains.
Contains 1 protein kinase domain. -
细胞定位
Membrane. - Information by UniProt
图片
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Functional Studies - Recombinant human ROS1 protein (ab125624)The specific activity of ROS1 (ab125624) was determined to be 610 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human ROS1 protein (ab125624)SDS PAGE analysis of ab125624 -
SDS-PAGE - Recombinant human ROS1 protein (ab125624)SDS PAGE analysis of ab125624 -
Functional Studies - Recombinant human ROS1 protein (ab125624)Sample Kinase Assay showing the specific activity of ab125624 as 640 nmol/min/mg. -
SDS-PAGE - Recombinant human ROS1 protein (ab125624)SDS-PAGE analysis of ab125624.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab125624 尚未被引用在任何文献中。