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重组人RHEB蛋白(ab78768)

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SDS-PAGE - Recombinant Human RHEB protein (ab78768)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Tags: T7 tag N-Terminus
    • Suitable for: SDS-PAGE

    描述

    • 产品名称

      重组人RHEB蛋白
      参阅全部 RHEB 蛋白酶

    • 纯度

      > 95 % SDS-PAGE.
      ab78768 is purified using conventional chromatography techniques.

    • 表达系统

      Escherichia coli

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MASMTGGQQM GRGSASMPQS KSRKIAILGY RSVGKSSLTI QFVEGQFVDS YDPTIENTFT KLITVNGQEY HLQLVDTAGQ DEYSIFPQTY SIDINGYILV YSVTSIKSFE VIKVIHGKLL DMVGKVQIPI MLVGNKKDLH MERVISYEEG KALAESWNAA FLESSAKENQ TAVDVFRRII LEAEKMDGAA SQGKSSC

      • 标签

        T7 tag N-Terminus

    技术指标

    Our Abpromise guarantee covers the use of ab78768 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.0154% DTT, 0.242% Tris, 10% Glycerol (glycerin, glycerine)

    常规信息

    • 别名

      • Ras homolog enriched in brain 2, formerly
      • GTP binding protein Rheb
      • GTP-binding protein Rheb
      • MGC111559
      • Ras homolog enriched in brain
      • Ras homolog enriched in brain 2
      • Rheb
      • RHEB 2
      • RHEB_HUMAN
      • RHEB2
      • RHEB2, formerly
      see all

    • 功能

      Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.

    • 组织特异性

      Ubiquitous. Highest levels observed in skeletal and cardiac muscle.

    • 序列相似性

      Belongs to the small GTPase superfamily. Rheb family.

    • 翻译后修饰

      Farnesylation is important for efficiently activating mTORC1-mediated signaling.

    • 细胞定位

      Cell membrane.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human RHEB protein (ab78768)
      SDS-PAGE - Recombinant Human RHEB protein (ab78768)
      15% SDS-PAGE showing ab76768 at approximately 22kDa (3µg).

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (1)

    发表研究结果有使用 ab78768？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab78768 被引用在 1 文献中.

    • Chalkiadaki K  et al. Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1. Brain N/A:N/A (2022). PubMed: 36315645

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