AB271504

重组人 RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) 蛋白 (Active) (His N-Term, DDDDK N-Term)

Name: 重组人RBBP4 + EED + SUZ12 + AEBP2 + EZH2 (mutated P132S)蛋白(活性) (ab271504)| Abcam中文官网
Brand: Abcam Limited
SKU: AB271504
Price: 6400 CNY
Availability: InStock

Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term)

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Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) is a Human Full Length protein, in the 2 to 425 aa range, expressed in Baculovirus infected Sf9 cells, with >90%, suitable for SDS-PAGE, FuncS.

查看别名

RBAP48, RBBP4, Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, CAF-1 subunit C, CAF-I 48 kDa subunit, CAF-I p48, RBBP-4

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Functional Studies - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

FuncS

Supplier Data

Functional Studies - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

Specific activity of ab271504.

SDS-PAGE - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

SDS-PAGE analysis of 4.35 μg ab271504.

关键信息

纯度

>90% SDS-PAGE

表达系统

Baculovirus infected Sf9 cells

应用

SDS-PAGE, FuncS

applications

生物活性

Yes

生物学活性

Specific Activity: 0.08 pmol/min/μg.

访问

Q09028

不含动物源

不含载体蛋白

种属

Human

存储溶液

pH: 8 Preservative: 1.36% Imidazole Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.63% Tris HCl, 0.02% Potassium chloride

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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序列信息

[{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"48 kDa","actualMolecularWeight":null,"aminoAcidEnd":425,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q09028","tags":[{"tag":"His","terminus":"N-Terminus"}]},{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"51 kDa","actualMolecularWeight":null,"aminoAcidEnd":441,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"O75530","tags":[{"tag":"DDDDK","terminus":"N-Terminus"}]},{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"53 kDa","actualMolecularWeight":null,"aminoAcidEnd":517,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q6ZN18","tags":[{"tag":"His","terminus":"N-Terminus"}]},{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"86 kDa","actualMolecularWeight":null,"aminoAcidEnd":746,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q15910","tags":[{"tag":"His","terminus":"N-Terminus"}]},{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"87 kDa","actualMolecularWeight":null,"aminoAcidEnd":739,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q15022","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

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性能和储存信息

运输条件

Dry Ice

储存信息

Avoid freeze / thaw cycle

True

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特殊说明

形式

Liquid

附加说明

Affinity purified.

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常规信息

功能

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (PubMed : 10866654). Component of the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair (PubMed : 8858152). Component of the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression (PubMed : 9150135). Component of the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling (PubMed : 16428440, PubMed : 28977666, PubMed : 39460621). Component of the PRC2 complex, which promotes repression of homeotic genes during development (PubMed : 29499137, PubMed : 31959557). Component of the NURF (nucleosome remodeling factor) complex (PubMed : 14609955, PubMed : 15310751).

序列相似性

Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.

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产品实验方案

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information RBBP4

其他靶点

SUZ12,,EED,

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重组人 RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) 蛋白 (Active) (His N-Term, DDDDK N-Term)

Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term)

Functional Studies - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

SDS-PAGE - Recombinant human RBBP4+EED+SUZ12+AEBP2+EZH2 (mut P132S) protein (Active) (His N-Term, DDDDK N-Term) (AB271504)

关键信息

纯度

表达系统

标签

应用

生物活性

生物学活性

访问

不含动物源

不含载体蛋白

种属

存储溶液