重组人PXR蛋白(ab82082)
Key features and details
- Expression system: Baculovirus infected insect cells
- Purity: > 90% Affinity purified
- Suitable for: GSA
描述
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产品名称
重组人PXR蛋白
参阅全部 PXR 蛋白酶 -
生物活性
1 unit equals 1 nanogram of purified protein. ab82082 binds to DNA as a heterodimer with RXR alpha; 1000U (1ug) required. -
纯度
> 90 % Affinity purified.
ab82082 is purified by an affinity column in combination with FPLC chromatography and is greater than 90% homogeneous. ab82082 contains no detectable proteases, DNase and RNase activity. -
表达系统
Baculovirus infected insect cells -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human
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技术指标
Our Abpromise guarantee covers the use of ab82082 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Gel Supershift Assays
EMSA
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形式
Liquid -
补充说明
1 unit equals 1 nanogram of purified protein. ab82082 binds to DNA as a heterodimer with RXR alpha; 1000U (1ug) required. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.9
Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- BXR
- Nr1i2
- NR1I2_HUMAN
see all -
功能
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. -
组织特异性
Expressed in liver, colon and small intestine. -
序列相似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab82082 尚未被引用在任何文献中。