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AB225984

重组人Putative 40S ribosomal蛋白-like (His tag)

Recombinant Human Putative 40S ribosomal protein-like (His tag)

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Recombinant Human Putative 40S ribosomal protein-like (His tag) is a Human Full Length protein, in the 1 to 176 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

查看别名

RPS10L, RPS10P5, Putative ribosomal protein eS10-like, Putative 40S ribosomal protein S10-like

1 Images
SDS-PAGE - Recombinant Human Putative 40S ribosomal protein-like (His tag) (AB225984)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Putative 40S ribosomal protein-like (His tag) (AB225984)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab225984 with 5% enrichment gel and 15% separation gel.

关键信息

纯度

>90% SDS-PAGE

表达系统

Escherichia coli

标签

6x His tag N-Terminus SUMO tag N-Terminus

应用

SDS-PAGE

applications

生物活性

No

访问

Q9NQ39

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"linker":null,"sequence":"MLMPKKNRIAIHELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGCVKEQFAWRHFYWYLTNEGSQYLRDYLHLPPEIVPATLHLPPEIVPATLHRSRPETGRPRPKGLEGKRPARLTRREADRDTYRRCSVPPGADKKAEAGAGSATEFQFRGRCGRGRGQPPQ","proteinLength":"Full Length","predictedMolecularWeight":"36.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":176,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9NQ39","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"SUMO","terminus":"N-Terminus"}]}]

性能和储存信息

形式
Liquid
运输条件
Blue Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The Putative 40S ribosomal protein-like sometimes referred to as RPL40-like functions as a structural component within the ribosomal subunit involved in translation. Its molecular weight is approximately 40 kDa. This protein localizes extensively in the cytoplasm specifically integrating into the small ribosomal subunit. Expression occurs widely across various tissues indicating a general role in protein synthesis.
Biological function summary

The Putative 40S ribosomal protein-like participates in the formation of the ribosome complex which is important for the translation of mRNA into proteins. As part of the ribosomal machinery this protein plays a role in ensuring the accuracy of translation and the efficient production of polypeptides. The interaction within the ribosome highlights its involvement in maintaining cellular protein homeostasis which is important for cell growth and function.

Pathways

The Putative 40S ribosomal protein-like integrates into the protein synthesis process contributing to the mTOR signaling pathway. The mTOR pathway regulates cell growth proliferation and survival and the protein's role links to its coordination in translation regulation. It also interacts with various translational factors such as eIF3 and eIF4 promoting efficient ribosomal initiation and elongation during protein synthesis.

Research links abnormal expression of ribosomal proteins including the Putative 40S ribosomal protein-like to certain cancers and hereditary ribosomopathies. Alterations in its expression or function may influence tumorigenesis due to disrupted protein synthesis and cell cycle control. Additionally RPL40-like can interact with other ribosomal proteins like RPL5 and RPL11 which are associated with Diamond-Blackfan anemia a disorder resulting from defective ribosome function.

常规信息

序列相似性

Belongs to the eukaryotic ribosomal protein eS10 family.

产品实验方案

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