重组人PROX1蛋白(ab54337)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
描述
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产品名称
重组人PROX1蛋白 -
纯度
> 95 % SDS-PAGE.
>95% by SDS-PHAGE & silver stain. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYT RYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAIND GVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNA IIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE -
预测分子量
22 kDa -
氨基酸
547 to 737
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技术指标
Our Abpromise guarantee covers the use of ab54337 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Lyophilized -
补充说明
This product can be used as a positive control e.g. in Western analysis.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituent: PBS
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复溶Reconstitute in water to a concentration not lower than 50 µg/ml.
常规信息
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别名
- Homeobox prospero like protein
- Homeobox prospero like protein PROX1
- Homeobox prospero-like protein PROX1
see all -
功能
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. -
组织特异性
Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas. -
序列相似性
Belongs to the Prospero homeobox family.
Contains 1 Prospero-type homeobox DNA-binding domain. -
结构域
The prospero-type homeobox DNA-binding domain is essential for repression of RORG transcriptional activator activity. -
细胞定位
Nucleus. RORG promotes its nuclear localization. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human PROX1 protein (ab54337)
SDS-PAGE analysis of recombinant human PROX1 protein fragment (ab54337). The sample was loaded in 15% SDS-polyacrylamide gel under reducing conditions and stained with Coomassie blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab54337 尚未被引用在任何文献中。