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Cardiovascular Angiogenesis Angiogenic Factors

重组人Prokineticin 2/PK2蛋白(ab50154)

  • Datasheet
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Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 0.100 Eu/µg
  • Suitable for: SDS-PAGE

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描述

  • 产品名称

    重组人Prokineticin 2/PK2蛋白
    参阅全部 Prokineticin 2/PK2 蛋白酶
  • 纯度

    > 95 % SDS-PAGE.
    Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 内毒素水平

    < 0.100 Eu/µg
  • 表达系统

    Escherichia coli
  • 蛋白长度

    Protein fragment
  • 无动物成分

    No
  • 性质

    Recombinant
    • 种属

      Human
    • 序列

      AVITGACDKD SQCGGGMCCA VSIWVKSIRI CTPMGKLGDS CHPLTRKVPF FGRRMHHTC PCLPGLACLR TSFNRFICLA QK

相关产品

  • Related Products

    • Anti-Prokineticin 2/PK2 antibody (ab87360)

技术指标

Our Abpromise guarantee covers the use of ab50154 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式

    Lyophilized
  • 补充说明

     This product was previously labelled as Prokineticin 2

     

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • 复溶
    For lot specific reconstitution information please contact our Scientific Support Team.

常规信息

  • 别名

    • BV8
    • Bv8 homolog
    • MIT1
    • PK2
    • PROK2
    • PROK2_HUMAN
    • Prokineticin-2
    • Protein Bv8 homolog
    see all
  • 功能

    May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
  • 组织特异性

    Expressed in the testis and, at low levels, in the small intestine.
  • 疾病相关

    Defects in PROK2 are the cause of Kallmann syndrome type 4 (KAL4) [MIM:610628]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. KAL4 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip/palate, selective tooth agenesis, and bimanual synkinesis.
  • 序列相似性

    Belongs to the AVIT (prokineticin) family.
  • 细胞定位

    Secreted.
  • Target information above from: UniProt accession Q9HC23 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

实验方案

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

数据表及文件

  • Datasheet download

    Download

文献 (0)

发表研究结果有使用 ab50154?请让我们知道,以便我们可以引用本数据表中的参考文章。

ab50154 尚未被引用在任何文献中。

客户评价及客户问答

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Question

I have been unable to find an appropriate protocol for the reconstitution of the lyophilised product into an aqueous solution. Is there such a protocol, if so where may I find it?

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Abcam community

Verified customer

Asked on Feb 14 2008

Answer

Thank you for your enquiry. Please centrifuge the vial prior to opening. Then, the reconstitution can be performed in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future use. If there is anything else that I can help you with, please do not hesitate to contact me.

Read More

Abcam Scientific Support

回复于 Feb 14 2008

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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