重组人PRMT2/HMT1蛋白(Tagged) (ab271718)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 90% SDS-PAGE
- Tags: DDDDK tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人PRMT2/HMT1蛋白(Tagged)
参阅全部 PRMT2/HMT1 蛋白酶 -
纯度
>= 90 % SDS-PAGE.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
ATSGDCPRSE SQGEEPAECS EAGLLQEGVQ PEEFVAIADY AATDETQLSF LRGEKILILR QTTADWWWGE RAGCCGYIPA NHVGKHVDEY DPEDTWQDEE YFGSYGTLKL HLEMLADQPR TTKYHSVILQ NKESLTDKVI LDVGCGTGII SLFCAHYARP RAVYAVEASE MAQHTGQLVL QNGFADIITV YQQKVEDVVL PEKVDVLVSE WMGTCLLFEF MIESILYARD AWLKEDGVIW PTMAALHLVP CSADKDYRSK VLFWDNAYEF NLSALKSLAV KEFFSKPKYN HILKPEDCLS EPCTILQLDM RTVQISDLET LRGELRFDIR KAGTLHGFTA WFSVHFQSLQ EGQPPQVLST GPFHPTTHWK QTLFMMDDPV PVHTGDVVTG SVVLQRNPVW RRHMSVALSW AVTSRQDPTS QKVGEKVFPI WR -
预测分子量
50 kDa -
氨基酸
2 to 433 -
标签
DDDDK tag N-Terminus -
额外的序列信息
NM_206962
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技术指标
Our Abpromise guarantee covers the use of ab271718 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine)
100 µg/ml DDDDK peptide
常规信息
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别名
- ANM2_HUMAN
- EC 2.1.1.
- histone arginine N methyltransferase PRMT2
see all -
功能
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. -
组织特异性
Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord. -
序列相似性
Belongs to the protein arginine N-methyltransferase family.
Contains 1 SH3 domain. -
细胞定位
Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human PRMT2/HMT1 protein (Tagged) (ab271718)
SDS-PAGE analysis of ab271718.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271718 尚未被引用在任何文献中。