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重组人PEN2蛋白(ab132019)

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SDS-PAGE - Recombinant Human PEN2 protein (ab132019)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: WB, SDS-PAGE, ELISA

    描述

    • 产品名称

      重组人PEN2蛋白
      参阅全部 PEN2 蛋白酶

    • 表达系统

      Wheat germ

    • Accession

      Q9NZ42

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQ SQIKGYVWRSAVGFLFWVIVLTSWITIFQIYRPRWGALGDYLSFTIPLGT P

      • 预测分子量

        37 kDa including tags

      • 氨基酸

        1 to 101

    技术指标

    Our Abpromise guarantee covers the use of ab132019 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      Western blot

      SDS-PAGE

      ELISA

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    常规信息

    • 别名

      • Gamma secretase subunit PEN 2
      • Gamma Secretase Subunit PEN2
      • Gamma-secretase subunit PEN-2
      • Hematopoietic stem/progenitor cells protein MDS033
      • MDS033
      • MSTP064
      • PEN 2
      • PEN2_HUMAN
      • Presenilin Enhancer 2
      • Presenilin enhancer 2 homolog
      • Presenilin enhancer protein 2
      • PSEN2
      • psenen
      see all

    • 功能

      Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    • 组织特异性

      Widely expressed. Expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.

    • 序列相似性

      Belongs to the PEN-2 family.

    • 细胞定位

      Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human PEN2 protein (ab132019)
      SDS-PAGE - Recombinant Human PEN2 protein (ab132019)
      12.5% SDS-PAGE stained with Coomassie Blue showing ab132019 at approximately 36.85 kDa.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab132019？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab132019 尚未被引用在任何文献中。

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