重组人PDGFR alpha蛋白(ab84797)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 90% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: WB, Functional Studies
描述
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产品名称
重组人PDGFR alpha蛋白
参阅全部 PDGFR alpha 蛋白酶 -
生物活性
Specific activity: 12nmol/min/mg.
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纯度
> 90 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
95 kDa -
氨基酸
550 to 1089 -
标签
GST tag N-Terminus -
额外的序列信息
Recombinant fragment of Human PDGF Receptor alpha (550-end) (cytoplasmic domain).
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相关产品
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Related Products
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Substrate reagent
技术指标
Our Abpromise guarantee covers the use of ab84797 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
Functional Studies
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形式
Liquid -
补充说明
ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- Alpha-type platelet-derived growth factor receptor
- CD140 antigen-like family member A
- CD140a
see all -
功能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
组织特异性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
疾病相关
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
序列相似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
细胞定位
Membrane. - Information by UniProt
图片
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Functional Studies - Recombinant human PDGFR alpha protein (ab84797)The specific activity of PDGFR alpha (ab84797) was determined to be 12.5 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human PDGFR alpha protein (ab84797)SDS PAGE analysis of ab84797 -
SDS-PAGE - Recombinant human PDGFR alpha protein (ab84797)SDS PAGE analysis of ab84797 -
Functional Studies - Recombinant human PDGFR alpha protein (ab84797)Activity of ab84797 -
SDS-PAGE - Recombinant human PDGFR alpha protein (ab84797)SDS Page analysis of ab84797
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab84797 尚未被引用在任何文献中。