重组人PDE4B蛋白(ab125582)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 70% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人PDE4B蛋白
参阅全部 PDE4B 蛋白酶 -
生物活性
The specific activity of ab125582 was determined to be 538 nmol/min/mg.
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纯度
>= 70 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
78 kDa including tags -
氨基酸
305 to 736 -
标签
GST tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab125582 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- 5''-cyclic phosphodiesterase 4B
- cAMP-specific 3''
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
see all -
功能
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. -
组织特异性
Expressed in brain, heart, lung and skeletal muscle. -
通路
Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. -
序列相似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. - Information by UniProt
图片
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Functional Studies - Recombinant human PDE4B protein (ab125582)The specific activity of PDE4B (ab125582) was determined to be 470 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human PDE4B protein (ab125582)SDS PAGE analysis of ab125582 -
SDS-PAGE - Recombinant human PDE4B protein (ab125582)SDS PAGE analysis of ab125582 -
SDS-PAGE - Recombinant human PDE4B protein (ab125582)SDS Page analysis of ab125582 -
Functional Studies - Recombinant human PDE4B protein (ab125582)The specific activity of ab125582 was determined to be 538 nmol/min/mg.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab125582 尚未被引用在任何文献中。