重组人PARIS蛋白(ab134852)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: T7 tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人PARIS蛋白 -
纯度
> 90 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
AEAVAAPISPWTMAATIQAMERKIESQAARLLSLEGRTGMAEKKLADCEK TAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPG SKGESPKEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPEVLSQIEQG KEPCNWRRPGPKIPDVPVDPSPGSGPPVPAPDLLMQIKQEGELQLQEQQA LGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTS WQTDLPPHHPSSACSDGTLKLNTAASTEDVKIVIKTEVQEEEVVATPVHP TDLEAHGTLFGPGQATRFFPSPAQEGAWESQGSSFPSQDPVLGLREPARP ERDMGELSPAVAQEETPPGDWLFGGVRWGWNFRCKPPVGLNPRTGPEGLP YSSPDNGEAILDPSQAPRPFNEPCKYPGRTKGFGHKPGLKKHPAAPPGGR PFTCATCGKSFQLQVSLSAHQRSCGAPDGSGPGTGGGGSGSGGGGGGSGG GSARDGSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERS KLIDHYRTHTGVRPFTCTVCGKSFIRKDHLRKHQRNHAAGAKTPARGQPL PTPPAPPDPFKSPASKGPLASTDLVTDWTCGLSVLGPTDGGDM -
氨基酸
2 to 644 -
标签
T7 tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab134852 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.00
Constituent: 0.32% Tris HCl
Buffer contains NaCl, KCl, EDTA, Arginine, DTT and Glycerol.
常规信息
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别名
- PARIS
- Parkin-interacting substrate
- Zinc finger protein 746
see all -
功能
Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. -
序列相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.
Contains 1 KRAB domain. -
翻译后修饰
Ubiquitinated by PARK2. 'Lys-48'-linked polyubiquitination by PARK2 leads to degradation by the proteasome and may play a key role in regulation of neuron death. -
细胞定位
Cytoplasm. Nucleus. Mainly localizes to the cytoplasm; probably translocates to the nucleus to repress selected genes. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab134852 尚未被引用在任何文献中。