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AB157887

重组人 Pancreatic alpha amylase 蛋白 (GST tag N-Terminus)

Recombinant Human Pancreatic alpha amylase protein (GST tag N-Terminus)

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Recombinant Human Pancreatic alpha amylase protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 511 aa range, expressed in Wheat germ, suitable for ELISA, WB.

查看别名

Pancreatic alpha-amylase, PA, AMY2A

1 Images
SDS-PAGE - Recombinant Human Pancreatic alpha amylase protein (GST tag N-Terminus) (AB157887)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Pancreatic alpha amylase protein (GST tag N-Terminus) (AB157887)

ab157887 on a 12.5% SDS-PAGE stained with Coomassie Blue.

关键信息

表达系统

Wheat germ

标签

GST tag N-Terminus

应用

WB, ELISA

applications

生物活性

No

访问

P04746

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"sequence":"MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":511,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P04746","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

性能和储存信息

运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Pancreatic alpha amylase also known as AMY2A is an enzyme responsible for catalyzing the hydrolysis of starch into sugars. This enzyme is an important amylase protein with a molecular mass of approximately 56 kDa. It is abundantly expressed in the pancreas of mammals playing a significant role in the digestive process. The product of its activity maltose contributes to carbohydrate digestion allowing for energy production in the body.
Biological function summary

Pancreatic alpha amylase assists in the breakdown of large polysaccharides into smaller maltose units. This enzyme can act independently and does not require a complex to function effectively. It carries out its activity primarily in the small intestine where it continues the digestive process initiated by salivary alpha amylase. This amylase protein ensures that starches consumed in the diet are converted into forms absorbable by the body contributing to overall metabolism.

Pathways

Pancreatic alpha amylase is a critical enzyme in the digestive pathway especially in the carbohydrate digestion and absorption pathway. Its activity complements that of other amylase enzymes including salivary alpha amylase to ensure efficient starch breakdown. Additionally pancreatic alpha amylase works in conjunction with proteins like glucose transporters which facilitate the entry of glucose into cells after starch breakdown.

The activity of pancreatic alpha amylase often links to conditions such as pancreatitis and type 2 diabetes. Elevated levels of this enzyme in the bloodstream can indicate acute pancreatitis highlighting its significance in diagnosing this disorder. In the context of diabetes altered pancreatic amylase activity can affect glucose metabolism. The enzyme's association with glucose-regulating proteins such as insulin makes it a focal point in understanding diabetic pathophysiology.

特殊说明

形式

Liquid

常规信息

序列相似性

Belongs to the glycosyl hydrolase 13 family.

产品实验方案

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