重组人p23蛋白(ab222791)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组人p23蛋白
参阅全部 p23 蛋白酶 -
生物活性
When ab222791 (4 μM) was added to Aha1-activated HSP90 (2 μM) in 33mM Hepes pH7.2, 30mM NaCl, 5mM MgCl2, 1mM DTT, 1.5mM ATP in a 100 μl reaction at 37°C, it eliminated all Aha1-mediated ATPase stimulation as well as intrinsic HSP90 ATPase activity. (This was an enzyme-linked ATP regeneration assay tracking loss of NADH absorbance at 340nm).
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纯度
> 90 % SDS-PAGE.
Affinity purified. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
SHMQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFK HLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNW LSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDS QDSDDEKMPDLE -
预测分子量
19 kDa -
氨基酸
1 to 160 -
额外的序列信息
Full-length protein with the addition of SH residues at the N-terminus.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab222791 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
pH: 7.20
Constituents: 10% Glycerol, 0.48% HEPES, 0.46% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- Co chaperone p23
- cPGES
- Cytosolic prostaglandin E synthase
see all -
功能
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. -
通路
Lipid metabolism; prostaglandin biosynthesis. -
序列相似性
Belongs to the p23/wos2 family.
Contains 1 CS domain. -
细胞定位
Cytoplasm. - Information by UniProt
图片
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SDS-PAGE - Recombinant human p23 protein (ab222791)SDS-PAGE of native human 23kDa p23 protein (ab222791)
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab222791 尚未被引用在任何文献中。