AB174557

重组人NIPSNAP1蛋白(denatured)

Name: 重组人NIPSNAP1蛋白(denatured) (ab174557)| Abcam中文官网
Brand: Abcam Limited
SKU: AB174557
Price: 5123 CNY
Availability: InStock

Recombinant Human NIPSNAP1 protein (denatured)

Be the first to review this product! Submit a review

(0 Publication)

Recombinant Human NIPSNAP1 protein (denatured) is a Human Full Length protein, in the 1 to 284 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

查看别名

Protein NipSnap homolog 1, NipSnap1, NIPSNAP1

1 Images

SDS-PAGE - Recombinant Human NIPSNAP1 protein (denatured) (AB174557)

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human NIPSNAP1 protein (denatured) (AB174557)

15% SDS-PAGE analysis of ab174557 (3 μg).

关键信息

纯度

>85% SDS-PAGE

表达系统

Escherichia coli

应用

SDS-PAGE

applications

生物活性

访问

Q9BPW8

不含动物源

不含载体蛋白

种属

Human

存储溶液

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl

storage-buffer

style

left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

style

left-column

style

left-column

序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ","proteinLength":"Full Length","predictedMolecularWeight":"35.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":284,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9BPW8","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

style

left-column

性能和储存信息

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

False

style

left-column

style

left-column

特殊说明

形式

Liquid

style

left-column

常规信息

功能

Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria (PubMed : 30982665). Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2) (PubMed : 30982665).

序列相似性

Belongs to the NipSnap family.

翻译后修饰

In response to mitochondrial stress, the precursor protein is ubiquitinated by the SIFI complex in the cytoplasm before mitochondrial import, leading to its degradation (PubMed:38297121). Within the SIFI complex, UBR4 initiates ubiquitin chain that are further elongated or branched by KCMF1 (PubMed:38297121).

style

left-column

产品实验方案

Visit the General protocols
Visit the Troubleshooting

style

left-column

靶点信息

See full target information NIPSNAP1

style

left-column

style

left-column

style

right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组人NIPSNAP1蛋白(denatured)

Recombinant Human NIPSNAP1 protein (denatured)

SDS-PAGE - Recombinant Human NIPSNAP1 protein (denatured) (AB174557)

关键信息

纯度

表达系统

标签

应用

生物活性

访问

不含动物源

不含载体蛋白

种属

存储溶液