重组人Neuritin蛋白(ab69755)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组人Neuritin蛋白 -
生物活性
Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/mL.
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纯度
> 98 % SDS-PAGE.
Purity is greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.100 ng/µg. -
内毒素水平
< 1.000 Eu/µg -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
M-AGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN -
预测分子量
19 kDa -
氨基酸
28 to 115
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab69755 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8oC for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20oC to -80oC.
常规信息
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别名
- Neuritin
- Neuritin 1
- NRN
see all -
功能
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. -
序列相似性
Belongs to the neuritin family. -
细胞定位
Cell membrane. Cell junction > synapse. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (3)
ab69755 被引用在 3 文献中.
- Hurst C et al. Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease. Mol Cell Proteomics 22:100542 (2023). PubMed: 37024090
- Gonzalez-Figueroa P et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell 184:1775-1789.e19 (2021). PubMed: 33711260
- Sato H et al. Thalamus-derived molecules promote survival and dendritic growth of developing cortical neurons. J Neurosci 32:15388-402 (2012). PubMed: 23115177
