重组人NACA1蛋白(ab113865)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS
描述
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产品名称
重组人NACA1蛋白 -
纯度
> 95 % SDS-PAGE.
ab113865 was purified by using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMPGEATETVPATEQELPQPQAETGSGTESD SDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAM SKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIED LSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM -
预测分子量
26 kDa including tags -
氨基酸
1 to 215 -
标签
His tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab113865 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Mass Spectrometry
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质谱法
MALDI-TOF -
形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
常规信息
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别名
- Alpha NAC
- Alpha-NAC
- Hom s 2.02
see all -
功能
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. -
组织特异性
Ubiquitously expressed. -
序列相似性
Belongs to the NAC-alpha family.
Contains 1 NAC-A/B (NAC-alpha/beta) domain.
Contains 1 UBA domain. -
翻译后修饰
Phosphorylation of Ser-43 by ILK during cell adhesion may promote nuclear localization. Phosphorylation of Thr-159 by GSK3B may promote proteasome mediated degradation (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cytoplasm. Nucleus. Predominantly cytoplasmic. Also found in nucleus. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human NACA1 protein (ab113865)
3ug by SDS-PAGE under reducing conditions and visualized by coomassie blue stain.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab113865 尚未被引用在任何文献中。