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重组人Myostatin Propeptide蛋白(ab49855)

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Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Active: Yes
  • Suitable for: SDS-PAGE

描述

  • 产品名称

    重组人Myostatin Propeptide蛋白
    参阅全部 Myostatin Propeptide 蛋白酶

  • 生物活性

    Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01–0.04 μg/ml in the presence of 50 ng/ml Myostatin.

  • 纯度

    > 98 % SDS-PAGE.

  • 表达系统

    Escherichia coli

  • Accession

    O14793

  • 蛋白长度

    Protein fragment

  • 无动物成分

    No

  • 性质

    Recombinant

    • 种属

      Human

    • 序列

      MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR

    • 预测分子量

      28 kDa

    • 氨基酸

      24 to 266

技术指标

Our Abpromise guarantee covers the use of ab49855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式

    Lyophilized
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    For lot specific reconstitution information please contact our Scientific Support Team.

常规信息

  • 别名

    • Cmpt
    • GDF-8
    • GDF8_HUMAN
    • Growth/differentiation factor 8
    • MSLHP
    • MSTN
    • MSTN myostatin
    • Myostatin
    • Myostatin Propeptide
    see all

  • 功能

    Acts specifically as a negative regulator of skeletal muscle growth.

  • 疾病相关

    Defects in MSTN are the cause of muscle hypertrophy (MSLHP) [MIM:614160]. MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.

  • 序列相似性

    Belongs to the TGF-beta family.

  • 细胞定位

    Secreted.
  • Information by UniProt

实验方案

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

文献 (0)

发表研究结果有使用 ab49855？请让我们知道，以便我们可以引用本数据表中的参考文章。

ab49855 尚未被引用在任何文献中。

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