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AB180279

重组人MMP23蛋白(denatured)

Recombinant Human MMP23 protein (denatured)

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Recombinant Human MMP23 protein (denatured) is a Human Fragment protein, in the 79 to 254 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

查看别名

MMP21, MMP22, MMP23B, Matrix metalloproteinase-23, MMP-23, Femalysin, MIFR-1, Matrix metalloproteinase-21, Matrix metalloproteinase-22, MMP-21, MMP-22

1 Images
SDS-PAGE - Recombinant Human MMP23 protein (denatured) (AB180279)
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Supplier Data

SDS-PAGE - Recombinant Human MMP23 protein (denatured) (AB180279)

15% SDS-PAGE analysis of ab180279 (3μg).

关键信息

纯度

>85% SDS-PAGE

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

SDS-PAGE

applications

生物活性

No

访问

O75900

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl

storage-buffer

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSYTLTPARLRWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPINHTDCLVSALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKALSQDELWGLHRLYG","proteinLength":"Fragment","predictedMolecularWeight":"22.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":254,"aminoAcidStart":79,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O75900","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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性能和储存信息

运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The protein MMP23 also known as matrix metalloproteinase-23 plays a role in tissue remodeling and cellular processes. MMP23 is unique due to its membrane-type structure distinguishing it from other MMP family members. The protein weighs approximately 44 kDa. MMP23 is mainly found in a variety of tissues including the testis ovary and placenta but its expression is notably less widespread compared to other metalloproteinases.
Biological function summary

Matrix metalloproteinase-23 contributes to modulating extracellular matrix degradation. Unlike some MMPs MMP23 is part of a transmembrane complex impacting localized tissue environments. It influences cellular growth and communication through its regulatory effects on the extracellular space. Such interactions play a part in processes like cell migration and signal transduction important for normal physiological and developmental activities.

Pathways

MMP23 participates in specific biochemical pathways important for tissue repair and immune response. One significant pathway is the extracellular matrix (ECM) remodeling pathway where MMP23 interacts with other metalloproteinases such as MMP2. Additionally MMP23's activity affects signaling pathways by altering the ECM components which can influence cellular behaviors linked to proliferation and apoptosis.

Matrix metalloproteinase-23 implicates its role in certain pathologies including cancer and inflammatory diseases. Its ability to modify the extracellular matrix associates it with tumor invasion and metastasis particularly through interactions with proteins like TIMP (tissue inhibitors of metalloproteinases). Inflammatory conditions also show altered MMP23 activity indicating its potential involvement in chronic inflammation pathophysiology.
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特殊说明

形式

Liquid

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常规信息

功能

Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).

序列相似性

Belongs to the peptidase M10A family.

翻译后修饰

N-glycosylated.. Proteolytic cleavage might yield an active form.

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产品实验方案

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靶点信息

Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
See full target information MMP23B
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搭配使用产品

Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

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Proteins & Peptides

AB180327

Recombinant Human MED3 protein (denatured)

SDS-PAGE - Recombinant Human MED3 protein (denatured) (AB180327)

  • 0
  • 0
Secondary Antibodies

AB97131

Goat Anti-Chicken IgY H&L

  • 0
  • 0
Primary Antibodies

AB181118

Anti-MMP23 antibody [EPR7769]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-MMP23 antibody [EPR7769] (AB181118)

  • 0
  • 0

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