重组人MGP蛋白(denatured) (ab113156)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人MGP蛋白(denatured)
参阅全部 MGP 蛋白酶 -
纯度
> 90 % SDS-PAGE.
ab113156 was purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMYESHESMESYELNPFINRRNANTFISPQQ RWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYF -
预测分子量
12 kDa including tags -
氨基酸
20 to 96 -
标签
His tag N-Terminus
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描述
重组人MGP蛋白
相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab113156 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine)
常规信息
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别名
- Cell growth inhibiting gene 36 protein
- Cell growth-inhibiting gene 36 protein
- GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX
see all -
功能
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. -
疾病相关
Defects in MGP are the cause of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. -
序列相似性
Belongs to the osteocalcin/matrix Gla protein family.
Contains 1 Gla (gamma-carboxy-glutamate) domain. -
翻译后修饰
Requires vitamin K-dependent gamma-carboxylation for its function. -
细胞定位
Secreted. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human MGP protein (denatured) (ab113156)15% SDS-PAGE showing ab113156 (3 µg) at approximately 11.8 kDa.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab113156 被引用在 1 文献中.
- Liu Q et al. Chondrocyte-derived exosomes promote cartilage calcification in temporomandibular joint osteoarthritis. Arthritis Res Ther 24:44 (2022). PubMed: 35164837