重组人MAX蛋白(ab95309)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: MS, SDS-PAGE, WB
描述
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产品名称
重组人MAX蛋白 -
纯度
> 90 % SDS-PAGE.
ab95309 is purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS LEHHHHHH -
预测分子量
19 kDa -
氨基酸
1 to 160 -
标签
His tag C-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab95309 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Mass Spectrometry
SDS-PAGE
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)
常规信息
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别名
- bHLHd4
- bHLHd5
- bHLHd6
see all -
功能
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. -
组织特异性
High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. -
疾病相关
Pheochromocytoma -
序列相似性
Belongs to the MAX family.
Contains 1 bHLH (basic helix-loop-helix) domain. -
翻译后修饰
Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes. -
细胞定位
Nucleus. Cell projection, dendrite. - Information by UniProt
图片
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Western blot - Recombinant Human MAX protein (ab95309)Ab68578 recognizes the tagged recombinant MAX protein (ab95309) which has an expected molecular weight of 24 kDa.
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SDS-PAGE - Recombinant Human MAX protein (ab95309)SDS-PAGE analysis of ab95309 (3µg).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab95309 被引用在 1 文献中.
- Struntz NB et al. Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chem Biol 26:711-723.e14 (2019). PubMed: 30880155