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重组人LEO1/RDL蛋白(ab132311)

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Western blot - Recombinant Human LEO1/RDL protein (ab132311)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: SDS-PAGE, WB, ELISA

    描述

    • 产品名称

      重组人LEO1/RDL蛋白

    • 表达系统

      Wheat germ

    • Accession

      Q8WVC0

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDER GDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDND PSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDK SDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDE RQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDER PQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADS DTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEE EPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED EEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSL HLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSAT HRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRE SQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIRE ERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANK KHKKYVISDEEEEDDD

      • 预测分子量

        102 kDa including tags

      • 氨基酸

        1 to 666

    技术指标

    Our Abpromise guarantee covers the use of ab132311 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      SDS-PAGE

      Western blot

      ELISA

    • 形式

      Liquid

    • 补充说明

      This product was previously labelled as LEO1.

       

    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    常规信息

    • 别名

      • Gm185
      • LEO1
      • LEO1_HUMAN
      • LOC123439
      • Paf1/RNA polymerase II complex component
      • Replicative senescence down regulated leo1 like protein
      • Replicative senescence down-regulated leo1-like protein
      • Replicative senescence downregulated leo1 like
      • RNA polymerase associated protein LEO1
      • RNA polymerase-associated protein LEO1
      • Senescence downregulated leo1 like
      see all

    • 功能

      The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.

    • 组织特异性

      Highly expressed in skeletal muscle and heart. Weakly expressed in placenta and liver.

    • 序列相似性

      Belongs to the LEO1 family.

    • 细胞定位

      Nucleus.
    • Information by UniProt

    图片

    • Western blot - Recombinant Human LEO1/RDL protein (ab132311)
      Western blot - Recombinant Human LEO1/RDL protein (ab132311)
      ab132311 on 12.5% SDS-PAGE stained with Coomassie blue.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab132311？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab132311 尚未被引用在任何文献中。

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